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HIV-1 Gag-specific exosome-targeted T cell-based vaccine stimulates effector CTL responses leading to therapeutic and long-term immunity against Gag/HLA-A2-expressing B16 melanoma in transgenic HLA-A2 mice

机译：HIV-1 Gag特异性外泌体靶向T细胞疫苗刺激效应CTL反应，导致转基因HLa-a2小鼠对Gag / HLa-a2表达B16黑素瘤的治疗性和长期免疫力

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Rong Wang; Yufeng Xie; Tuo Zhao; Xing Tan; Jianqing Xu; Jim Xiang;
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1. The Tat Protein Enhances CTL Responses and Therapeutic Immunity of Gag-Specific Exosome-Targeted T Cell-Based Gag/Tat-Texo Vaccine in Transgenic HLA-A2 Mice [J] . Aizhang Xu, Jie Wu, Yufeng Xie, World Journal of Vaccines . 2017,第2期

机译：TAT蛋白增强了转基因HLA-A2小鼠中的GAG特异性外出体靶向T细胞的GAG / TAT-TEXO疫苗的CTL响应和治疗性免疫
2. Novel CD8(+) T cell-based vaccine stimulates Gp120-specific CTL responses leading to therapeutic and long-term immunity in transgenic HLA-A2 mice [J] . Nanjundappa Roopa Hebbandi, Wang Rong, Xie Yufeng, Vaccine . 2012,第24期

机译：基于CD8（+）T细胞的新型疫苗可刺激Gp120特异性CTL反应，从而在转基因HLA-A2小鼠中产生治疗性和长期免疫性
3. Exosomal pMHC-I complex targets T cell-based vaccine to directly stimulate CTL responses leading to antitumor immunity in transgenic FVBneuN and HLA-A2/HER2 mice and eradicating trastuzumab-resistant tumor in athymic nude mice [J] . WangL., XieY., AhmedK.A., Breast cancer research and treatment. . 2013,第2期

机译：外泌体pMHC-1复合物靶向T细胞疫苗，直接刺激CTL反应，从而在转基因FVBneuN和HLA-A2 / HER2小鼠中产生抗肿瘤免疫力，并在无胸腺裸鼠中根除抗曲妥珠单抗的肿瘤
4. Transgenic 4-1BBL-engineered vaccine stimulates potent Gag-specific therapeutic and long-term immunity via increased priming of CD44+CD62Lhigh IL-7R+ CTLs with up- and downregulation of anti- and pro-apoptosis genes [O] . Rong Wang, Andrew Freywald, Yue Chen, 2015

机译：转基因4-1BBL工程疫苗通过增强CD44 + CD62Lhigh IL-7R + CTL的引发抗凋亡和促凋亡基因的上调和下调来刺激强效的Gag特异性治疗和长期免疫
5. HIV-1 Gag-specific exosome-targeted T cell-based vaccine stimulates effector CTL responses leading to therapeutic and long-term immunity against Gag/HLA-A2-expressing B16 melanoma in transgenic HLA-A2 mice [O] . Wang Rong, Xie Yufeng, Zhao Tuo, 2014

机译：HIV-1 Gag特异性针对外来体的T细胞疫苗可刺激效应CTL反应，从而导致转基因HLA-A2小鼠对表达Gag / HLA-A2的B16黑色素瘤具有治疗性和长期免疫性

HIV-1 Gag-specific exosome-targeted T cell-based vaccine stimulates effector CTL responses leading to therapeutic and long-term immunity against Gag/HLA-A2-expressing B16 melanoma in transgenic HLA-A2 mice

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